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Nootropics Tianeptine Sodium Salt Powder Intermediates
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Product Details:
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Detailed Product Description
| Product NamTianeptine Sodium Salte: | Tianeptine Sodium Salt | Type: | Nootropics |
|---|---|---|---|
| Cas No: | 30123-17-2 | Purity: | 99% Purity |
| MW: | 458.93 | Assay: | 99% |
| Storage: | Cool Dry Place | Shelf Life: | 2 Years |
| High Light: | Tianeptine Sodium Nootropic Powder,Intermediates Tianeptine Sodium Powder,Sodium Salt Nootropics Powder |
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High Purity Nootropics Tianeptine Sodium Salt Powder
Descriptions of of Tianeptine Sodium Salt:
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine is an atypical antidepressant. It is an agonist of the μ-opioid receptor (MOR; EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also has effects on the glutamate system. Tianeptine (30 mg/kg) decreases immobility in the forced swim test in wild-type, but not MOR knockout mice, indicating antidepressant-like activity dependent on MORs. It increases locomotor activity at a dose of 30, but not 10 mg/kg, in the open field test and increases paw withdrawal latency in the hot-plate test in mice. Tianeptine modulates AMPA receptor activity by increasing phosphorylation of the AMPA receptor GluR1 subunit in the frontal cortex and hippocampal CA3 region in mice. It prevents increases in glial glutamate transporter 1 (GLT-1) expression induced by chronic restraint stress in the hippocampal CA3 region in rats when administered at a dose of 10 mg/kg per day for 21 days.5It also reverses increases in extracellular glutamate levels induced by acute restraint stress in the basolateral nucleus of the amygdala in rats.
| Product Name: | Tianeptine sodium salt |
| CAS No: | 30123-17-2 |
| Molecular Formular: | C21H24ClN2NaO4S |
| Molecular Weight: | 458.93 |
| Melting point: | 1800C |
| Place of Origin: | China |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Color | White |
| Purity: | 99.90% |
| Packing: | 25kg/cartoon box |
| Application: | Intermediates |
| Storage: | Dry and cool place and keep away from strong light |
| Sample: | Available |
| Shelf life: | 2 years |
Function of Tianeptine Sodium Salt:
Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. IC50 Value:Target: 5-HT ReceptorTianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo.
Tianeptine is a tricyclic antidepressant that enhances serotonin uptake. This drug can affect neuroprotection, neuronal excitability, memory and anxiety. However, tianeptine is not linked to adverse psychomotor, cognitive, cardiovascular, sleep and bodyweight effects. The drug has a low tendency for abuse and has a positive pharmacokinetic profile.
Tianeptine is least involved in drug interaction as it is not metabolized by cytochrome P450 system in the liver. In hippocampus and amygdala, tianeptine is involved in glutamatergic transmission processes and elicits neuroplasticity.
Application of Tianeptine Sodium Salt:
1) Tianeptine Sodium Powder Improves Depressive Symptoms.
2) Tianeptine Sodium Powder Lessens Anxiety, Stress, and PTSD and Symptoms From Stress.
3) Tianeptine Sodium Powder Benefits Memory and Learning.
4) Tianeptine Sodium Powder is an Anti-inflammatory.
5) Tianeptine Sodium Powder decreases pain.
6) Tianeptine Sodium Powder Helps Treat Irritable bowel Syndrome.
7) Tianeptine Sodium Powder Reduces Asthma.
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
SHIPPING & DELIVERY
1. Packages are generally dispatched within approximately 3 days after receipt of payment.
2. we will provide you with a link & tracking number to track your package online. and send the few pictures with your order & details.
3. About the Custom clearance,we packed in disguise ways. We guarantee you safely and fast received the package
4. We confirm 99% clearance, If you can not received the package, we will arrange reshipment to you
If you interested our product, welcome to contact us WhatsApp: +86-188-2197-6359 or you can send details on chenfengbiotech@126.com
Contact Details
Xian ChenFeng Biotech Co., Ltd.
Contact Person: Hill Zhang
Tel: 86-188-2175-6359
Send your inquiry directly to us
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