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Cialis (tadalafil) is an expensive drug used to treat erection problems in men. It may also be used to treat the enlargement of the prostate gland. This drug is slightly more popular than comparable drugs. It is available in both brand and generic versions. Cialis is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Tadalafil 40mg is approved in the United States, Canada, and Japan as a once-daily therapy to improve exercise ability in patients with pulmonary arterial hypertension (PAH).
The pulmonary vascular lumen is decreased in PAH as a result of vasoconstriction and vascular remodeling, resulting in increased pulmonary artery pressure and pulmonary vascular resistance. Tadalafil causes pulmonary artery vasodilation, and inhibits vascular remodeling, thus lowering pulmonary arterial pressure and resistance. Right heart failure is the principal consequence of severe pulmonary arterial hypertension.
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