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Oral Steroids Exemestane 25 Mg Tablet,
Exemestane 25 Mg Tablet,
Aromasin 25mg Tablet
25mg * 30pcs Oral Aromasin Exemestane 99% Purity For Breast Cancer Fighting
Exemestane is a steroidal Aromatase Inhibitor (AI) that is most commonly known as Aromasin
Exemestane is officially classified as a steroidal suicide Aromatase Inhibitor, and carries the ability to
inhibit the aromatase enzyme, which is responsible for the production or conversion of testosterone to
estrogen. Exemestane has the ability to block aromatization, which in turn inhibits the production of
estrogen, and thereby lowers the body’s serum estrogen levels. This will prove useful to breast cancer
patients as breast cancer often feeds off the estrogen hormone. It will also prove useful to the anabolic
steroid user.Because it protects against estrogenic related side effects.
Many anabolic steroids have the ability to increase estrogen levels due to the aromatase process,
specifically the conversion of testosterone to estrogen. This can lead to gynecomastia and water
retention. Excess water retention can also promote high blood pressure when it becomes severe. Steroids that do not carry a strong estrogenic nature can also cause these effects, most notably gynecomastia if they carry a progestin nature.
Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.
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