C30H48O3 Human Steroid Hormones Testosterone Undecanoate CAS 5949-44-0

Anabolic Steroids powder Testosterone Undecanoate CAS 5949-44-0

Quick Details:

Testosterone undecanoate
English Synonyms: TESTOSTERONE UNDECANOATE;TESTOSTERONE UNDECANOILATE;17-beta-hydroxy-5-alpha-androstan-3-onundecanoate;testosterone,undecanoate(ester);andriol;4-ANDROSTEN-17BETA-OL-3-ONE 17-UNDECANOATE;4-ANDROSTEN-17-BETA-OL-3-ONE UNDECANOATE;17-[(1-oxoundecyl)oxy]-androst-4-en-3-one
CAS NO.: 5949-44-0
EINECS: 227-712-6
Assay: 98% min.
Molecular Formula: C30H48O3
Molecular weight: 456.70
Packing:1kg/tin
Character: White crystalline powder.
Usage: With testosterone, long-term for intramuscular injection androgens, maintain about 70 days.Oral absorption is rapid, the peak blood levels of 4 to 5 hours, but most by the intestinal wall and the liver was first metabolism, bioavailability is low;Intramuscular injection can avoid the first elimination.Clinical apply to men's sexual function reduce, aplastic anemia, etc.Primary or secondary testicular function impairment;Middle-aged and old male hormone deficient syndrome;Of infertility caused by raw essence dysfunction and aplastic anemia.

Description:
Testosterone undecanoate or testosterone undecylate, is anandrogen and anabolic steroid and a testosterone ester. It is used in androgen replacement therapyprimarily for the treatment of male hypogonadism, and has also been investigated for use as a male contraceptive. Unlike other testosterone esters, testosterone undecanoate is available in both oral and intramuscular formulations.[4] The Reandron 1000 formulation (Nebido in the United States) contains 1000 mg of testosterone undecanoate suspended in castor oil with benzyl benzoate for solubilisation and as apreservative, and is administered by intramuscular injection. As an excipient, benzyl benzoate has been reported as a cause of anaphylaxis in a case in Australia. Bayer includes this report in information for health professionals and recommends that physicians "should be aware of the potential for serious allergic reactions" to preparations of this type.In Australia, reports to ADRAC, which evaluates reports ofadverse drug reactions for the Therapeutic Goods Administration, show several reports of allergic issues since the anaphylaxis case from 2011.

Testosterone undecanoate is prescribed for adult males with deficiency or absence of testosterone due to primary hypogonadism or hypogonadotropic hypogonadism.

Testosterone undecanoate has a very long elimination half-life and mean residence time when given as adepot intramuscular injection.The elimination half-life and mean residence time of testosterone undecanoate are 2.5-fold and 4-fold longer than those of testosterone enanthate (the values for testosterone enanthate being 4.5 days and 8.5 days, respectively).

Effect:
Treating symptoms of low testosterone in men when the body does not make any testosterone or not enough testosterone (hypogonadism). It may also be used for other conditions.
Testosterone undecanoate is a male sex hormone. It works by replacing or supplementing the testosterone that is naturally made in the body.

Dosage:
Males over 18 years of age: The recommended dose of testosterone undecanoate is 750 mg (3 ml) intramuscularly; followed by 750 mg (3 ml) intramuscularly after 4 weeks, then 750 mg (3 ml) intramuscularly every 10 weeks thereafter.

Safe and effective use of testosterone undecanoate is not determined for males under 18 years of age.

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