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|Product Name:||Pregabalin||Cas No:||148553-50-8|
148553-50-8 API Raw Materials,
Pregabalin API Raw Materials,
Anti Epileptic Pregabalin Powder
API raw materials 99% purity high Quality Lyrica Pregabalin powder for Anti-epileptic Cas148553-50-8
Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults.It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in the European Union.It was designed as a more potent successor to gabapentin.
Recent studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgiaand spinal cord injury. In June 2007, pregabalin became the first medication approved by the U.S. Food and Drug Administration specifically for the treatment of fibromyalgia.
Product Name : Pregablin
Synonym: Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid
Appearance: White Crystal Powder
Usage: New antiepileptic drugs. Used in the treatment of peripheral neuropathy, or partial seizures adjuvant treatment.
|Appearance||White or almost white powder||White powder|
|Solubility||Practically insoluble in water, freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride||conform|
|Special optical rotation (dried substance)||78.0 to +84.0||81.0°|
|Impurities A, B and C||Impurity A: ≤0.15%||0.01%|
|Specified impurities: ≤0.10%||conform|
|relative substance||Unspecified impurities: ≤0.10%||0.09%|
|Total impurity: ≤0.3%||0.17%|
|Loss on drying||≤0.5%||0.20%|
|Assay (on dried basis)||97.5%~102%||99.57%|
1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
2. The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Can also be used to treat pain and anxiety.
Pregabalin, is a new type of GABA receptor agonists, can block the voltage dependence calcium channel to reduce the neurotransmitter release, mainly used for clinical treatment of peripheral neuropathy and auxiliary for the treatment of localized part seizures.
LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and titanium dioxide.
Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms, hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster). It is also used to treat fibromyalgia (a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep). Pregabalin is used with other medications to treat certain types of seizures in people with epilepsy. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body
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