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Muscle Gaining Testosterone Undecanoate Injection,
5949-44-0 Testosterone Undecanoate Injection,
Testosterone 250mg Injection
Muscle Gaining Injectable Testosterone Undecanoate Oil CAS 250mg/ml 10ml Per vial Cas 5949-44-0
Testosterone Undecanoate/Test unde Cas5949-44-0 powders administered orally generally enter the blood stream through the liver. When a steroid compound is given this way without some form of structural protection, it will be quickly broken down during the "first pass".
This process leaves very little steroid intact, basically deactivating the drug. Adding a methyl group (c-17 AA) to the structure is one way to protect it from this process, however stress is also placed on the liver as a result.
In some instances this stress can lead to actual damage to liver tissues, so the designers of this steroid sought another way to protect the testosterone molecule. With Testosterone Undecanoate/Test unde, this was accomplished by making a form of testosterone that would be absorbed through the lymphatic system. This is due to its high fat solubility brought about by the ester, and its suspension in oil.
Having the compound absorbed this way was thought to be very advantageous, as it allows the steroid to bypass the destructive first-pass through liver. This should permit the compound to enter the blood stream intact, without the need for a harsh chemical alteration. The ester breaks off once it is in circulation of course, yielding free active Pharmacokinetics of Oral Testosterone. In design this steroid appears to be undecanoate that of a completely liver safe and orally active form of testosterone.
What Is Testosterone Undecanoate?
Testosterone undecandoate might be prescribed for the treatment of hypogonadism in men, but more recently, the androgen has been used as a male contraceptive. Since the 1980s, researchers have been testing testosterone variations in an attempt to develop one. While this testosterone ester produces effective results in Asian men, the hormone requires the addition of other hormones to produce equally successful outcomes for men in other countries.
This ester of testosterone suppresses follicle stimulating hormone (FSH) and luteinizing hormone (LH), interfering with the signals required by the testes to produce sperm and resulting in lowered sperm counts. Men usually do not experience the full effects of treatment, however, until after the first two or three months of receiving the drug. Sperm counts then remain low for the duration of treatment. Counts generally return to normal anywhere from two to six months after cessation of treatment.
Chinese researchers first combined 200 milligrams (mg) of testosterone undecandoate with tea tree oil and administered the formula by intramuscular injection. Men received periodic injections over the course of 30 months. During the first trials, 80% to 90% of the men involved in the study developed sperm counts of less than one million sperm per milliliter (ml) of ejaculate. Normal sperm counts average around 20 million sperm per ml. After three months of treatment, the male contraceptive was 90% to 100% effective.
Testosterone Undecanoate or Testosterone Undecylate is an ester of Testosterone. Clinically, this hormone is used in androgen replacement therapy primarily for the treatment of male hypogonadism, and is currently under research for use as a male contraceptive. It is sold and distributed under the brand names Andriol, Undestor, Nebido, Pantestone, Restandol, Cernos Depot, Nebido-R and Reandron 1000. It aromatizes only minimally,which means little or no increased body fat. This makes it a welcome alternative for those who have problems with common Testosterone compounds. Testosterone Undecanoate is also suitable for pre-competition workouts. An additional advantage of Testosterone Undecanoate is non-aromatizing quality consists of the fact that the body's own hormone production is only affected after a long-term administration of very high dosages. Testosterone Undecanoate has only a low inhibitive effect on the hypothalamus so that the release of LHRH (luteinizing hormone releasing hormone) is rarely influenced. This is very important since LHRH stimulates the hypophysis to release gonadotropine which causes the Ledig's cells in the testes to produce Testosterone. Since Testosterone Undecanoate is quickly eliminated by the body it should also be considered for use before competitions requiring doping tests.
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